Methylene blue has drawn attention for its effects on mitochondrial energy production and cognitive function at low, pharmaceutical-grade doses. It's an emerging area of interest, not an established daily supplement, and it carries a serious interaction: it should never be combined with SSRIs, SNRIs, MAOIs, or other serotonergic medications, due to the risk of serotonin syndrome. Talk to one of our staff or your prescriber before starting if you take any mood or psychiatric medication.